Place the salmon skin side down on a cutting board. Using a sharp knife, cut it into 1 1/2 inch pieces. Carefully remove the skin from each piece.
Transfer the salmon pieces to a medium bowl and toss with olive oil, salt and pepper to coat.
Working in batches, add the salmon in a single layer to the air fryer basket. Depending on the size of your air fryer, you will probably need to do 2-3 batches. Air fry at 400° for 5-7 minutes per batch, until the internal temperature of the salmon has reached 145°F. Watch closely to prevent over-cooking.
While the salmon is air frying, prepare the spicy honey mustard by combining the mayo, mustard, honey, and chipotle chili pepper in a small bowl. Mix well.
Remove the salmon from the air fryer basket and gently toss it in honey mustard sauce, reserving some sauce for dipping.